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| 254595 | 85219127229 |
Sparsh Makhaik*, Wioletta K Rut-Schedlok, Shruti Choudhary*, Tulsi Upadhyay*, Chenzhou Hao*, Michael Westberg*, Cedric Bobst*, Euna Yoo*, Jasna Fejzo*, Michael Z Lin*, Matthew Bogyo*, Paul Thompson*, Marcin Drąg, Jeanne A Hardy*
A robust fluorogenic substrate for chikungunya virus protease (nsP2) activity. Protein Science 2025 vol. 34, nr 3, art. e70069, s. 1-16.
| 2025 | |
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2
| 255262 | 85216607996 |
Griffin J. Davis*, Anthony O Omole*, Yejin Jung*, Wioletta K Rut-Schedlok, Ronald Holewinski*, Kiall F Suazo*, Hong-Rae Kim*, Mo Yang*, Thorkell Andresson*, Marcin Drąg, Euna Yoo*
Chemical tools to define and manipulate interferon-inducible Ubl protease USP18. Nature Communications 2025 vol. 16, art. 957, s. 1-17.
| 2025 | |
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3
| 251558 | 85201418272 |
Wioletta K. Rut-Schedlok, Katarzyna M Groborz, Xinyuanyuan Sun*, Rolf Hilgenfeld*, Marcin Drąg
Profiling of coronaviral Mpro and enteroviral 3Cpro specificity provides a framework for the development of broad-spectrum antiviral compounds. Protein Science 2024 vol. 33, nr 9, art. e5139, s. 1-9.
| 2024 | |
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4
| 251555 | 85175731179 |
Fernanda R. Rocho*, Scott J Snipas*, Anwar Shamim*, Wioletta K Rut-Schedlok, Marcin Drąg, Carlos A Montanari*, Guy S Salvesen*
Differential specificity of SARS-CoV-2 main protease variants on peptide versus protein-based substrates. FEBS Journal 2024 vol. 291, nr 1, s. 61-69.
| 2024 | |
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5
| 250862 | 85200004634 |
Matthew W. Mahoney*, Jonathan Helander*, Anoopjit S Kooner*, Mariah Norman*, Vishnu C Damalanka*, Paolo De Bona*, Paulina M Kasperkiewicz-Wasilewska, Wioletta K Rut-Schedlok, Marcin Ł Poręba, Maithri M Kashipathy*, Kevin P Battaile*, Scott Lovell*, Anthony J O'Donoghue*, Charles S Craik*, Marcin Drąg, James W Janetka*
Use of protease substrate specificity screening in the rational design of selective protease inhibitors with unnatural amino acids: application to HGFA, matriptase, and hepsin. Protein Science 2024 vol. 33, nr 8, art. e5110, s. 1-19.
| 2024 | |
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6
| 245287 | 85174463058 |
Patrick Y. A. Reinke*, Edmarcia Elisa de Souza*, Sebastian Günther*, Sven Falke*, Julia Lieske*, Wiebke Ewert*, Jure Loboda*, Alexander Herrmann*, Aida Rahmani Mashhour*, Katarina Karničar*, Aleksandra Usenik*, Nataša Lindič*, Andreja Sekirnik*, Viviane F Botosso*, Gláucia M. M Santelli*, Josana Kapronezai*, Marcelo V de Araújo*, Tainá T Silva-Pereira*, Antônio F de Souza Filho*, Mariana S Tavares*, Lizdany Flórez-Álvarez*, Danielle B. L de Oliveira*, Edison L Durigon*, Paula R Giaretta*, Marcos B Heinemann*, Maurice Hauser*, Brandon Seychell*, Hendrik Böhler*, Wioletta K Rut-Schedlok, Marcin Drąg, Tobias Beck*, Russell Cox*, Henry N Chapman*, Christian Betzel*, Wolfgang Brehm*, Winfried Hinrichs*, Gregor Ebert*, Sharissa L Latham*, Ana M de Sá Guimarães*, Dusan Turk*, Carsten Wrenger*, Alke Meents*
Calpeptin is a potent cathepsin inhibitor and drug candidate for SARS-CoV-2 infections. Communications Biology 2023 vol. 6, art. 1058, s. 1-13.
| 2023 | |
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7
| 245290 | 85180404159 |
Dominika Staniec*, Wioletta K Rut-Schedlok, Marcin Drąg, Michał Burmistrz*, Michael Kitching*, Jan Potempa*
Mapping the substrate-binding subsite specificity of a Porphyromonas gingivalis Tpr peptidase. Acta Biochimica Polonica 2023 vol. 70, nr 4, s. 963-969.
| 2023 | |
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8
| 240087 | 85161201792 |
Mikołaj A. Żmudziński, Wioletta K Rut-Schedlok, Kamila Olech*, Jarosław M Granda*, Mirosław Giurg, Małgorzata Burda-Grabowska*, Rafał Kaleta*, Michala Zgarbova*, Renata Kasprzyk*, Linlin Zhang*, Xinyuanyuan Sun*, Zongyang Lv*, Digant Nayak*, Małgorzata Kęsik-Brodacka*, Shaun K Olsen*, Jan Weber*, Rolf Hilgenfeld*, Jacek Jemielity*, Marcin Drąg
Ebselen derivatives inhibit SARS-CoV-2 replication by inhibition of its essential proteins: PLpro and Mpro proteases, and nsp14 guanine N7-methyltransferase. Scientific Reports 2023 vol. 13, art. 9161, s. 1-16.
| 2023 | |
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9
| 239294 | 85151156004 |
Sizhu A. Chen*, Elena Arutyunova*, Jimmy Lu*, Muhammad Bashir Khan*, Wioletta K Rut-Schedlok, Mikołaj A Żmudziński, Shima Shahbaz*, Jegan Iyyathurai*, Eman W Moussa*, Zoe Turner*, Bing Bai*, Tess Lamer*, James A Nieman*, John C Vederas*, Olivier Julien*, Marcin Drąg, Shokrollah Elahi*, Howard S Young*, M. Joanne Lemieux*
SARS-CoV‑2 Mpro protease variants of concern display altered viral substrate and cell host target galectin-8 processing but retain sensitivity toward antivirals. ACS Central Science 2023 vol. 9, nr 4, s. 696-708.
[Publikacja zarejestrowana jako preonline dn. 22.03.2023, rok zaliczenia 2023.
Wersja ostateczna zarejestrowana 02.06.2023, rok zaliczenia 2023.]
| 2023 | |
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10
| 237729 | 85142642358 |
Radosław Gładysz, Natalia E Małek-Chudzik, Wioletta K Rut-Schedlok, Marcin Drąg
Investigation of the P1′ and P2′ sites of IQF substrates and their selectivity toward 20S proteasome subunits. Biological Chemistry 2023 vol. 404, nr 2/3, s. 221-227.
[Publikacja zarejestrowana jako preonline dn. 17.11.2022, rok zaliczenia 2022.
Wersja ostateczna zarejestrowana 03.04.2023, rok zaliczenia 2023.]
| 2023 | |
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